Ostinel Injections
(Sodium hyaluronate -hyaluronic acid)
DUROLANE is a single-injection hyaluronic acid treatment for knee osteoarthritis
DUROLANE is a unique, single-injection hyaluronic acid therapy that provides long-lasting pain relief from knee osteoarthritis. Hyaluronic acid (HA) in the knee acts as a lubricant and shock-absorber. The HA in DUROLANE is made with the same material.
What makes DUROLANE different is its concentration of hyaluronic acid, which has been carefully stabilized to resist degradation, extending the time DUROLANE stays in the joint and adding to its long-lasting effect.
Introduced worldwide in 2001, DUROLANE has been tested in more clinical studies than any other single-injection hyaluronic therapy on the market. It is proven safe for repeated courses of therapy and provides longer-lasting pain relief versus steroid injections.11 The hyaluronic acid in DUROLANE is also derived from a nonanimal source to reduce any risk of allergic reaction.
How does
Durolane work?
Hyaluronic acid is a molecule found naturally throughout the human body. It is an important component of joint fluid, called synovial fluid, which provides lubrication and cushioning for normal, healthy knees.
When you have osteoarthritis of the knee, the hyaluronic acid breaks down and becomes diluted. This reduces its natural elastic properties, which can further degrade cartilage tissue and cause increased joint pain.15
The hyaluronic acid in DUROLANE has the same composition as the natural hyaluronic acid your body produces, but it’s in a highly concentrated formulation that’s been uniquely stabilized to help resist the degradation caused by osteoarthritis.10 DUROLANE is administered as a single-injection directly into the knee.13
FAQ’s
How do I know if I have osteoarthritis in my knee?
You may have knee osteoarthritis if you experience one or more of the following common signs and symptoms26:
Sore knee after overuse or inactivity
Knee stiffness after resting or in the morning
Pain when moving your knee
Pain when climbing stairs or getting up from a chair
Knee pain that prevents you from exercising your leg
Grating or catching sensation when moving your knee
Knee pain that feels worse in the evening after a day’s activity
Deterioration of coordination due to knee pain and stiffness
Weakened thigh muscles
How is osteoarthritis different from other kinds of arthritis?
There are too many types of arthritis to list here (for a complete list, go to www.arthritis.org). Osteoarthritis refers to the condition caused by the breakdown or degeneration of the cartilage and fluid that cushion and lubricate the bones in your joints. Osteoarthritis can occur in any joint, but osteoarthritis of the knee is the most common type, affecting more than 10 million Americans.
Are all knee injection therapies for osteoarthritis the same?
No, there are different classes of injectable therapies that may be used to treat osteoarthritis in your knee. For example, steroid injections (such as cortisone) may help relieve knee pain and swelling temporarily. Opioids, such as morphine, are a class of drug with a very strong painkilling effect. On the other hand, hyaluronic acid injections like DUROLANE are designed to supplement the lost hyaluronic acid in the synovial fluid in your knee joint, which provides cushioning and lubrication.